The aim of the present study was to specify the risk factors for surgical treatment of BCLM. We evaluated the effects of patient age, time interval between the breast cancer and BCLM surgery, the type of surgical procedure, histopathological findings of the primary tumor, the number and overall diameter of BCLMs, the presence of resectable extra-hepatic metastases, and local tumor recurrence after breast cancer surgery on patients' overall OS and progression-free survival PFS. Breast cancer is the most frequent malignant disease affecting women and is the third most frequent malignant disease worldwide. In , approximately 40, deaths from this disease were registered in the USA 1. The incidence of breast cancer in the Czech Republic has continuously increased, although mortality from this disease has significantly decreased 2. Liver metastases usually occur together with other distant metastases, primarily involving the lungs and bones.
Female breast cancer survival continues to fall beyond five years after diagnosis. Download this data [xls] Download this data [ppt] Download this data [pdf]. Cancer survival statistics for common cancers in the UK.
Metastatic breast cancer also called stage IV or advanced breast cancer is not a specific type of breast cancer. It's the most advanced stage of breast cancer. Metastatic breast cancer is breast cancer that has spread beyond the breast and nearby lymph nodes to other organs in the body most often the bones, lungs, liver or brain. For example, breast cancer that has spread to the bones is still breast cancer not bone cancer. It may also be called metastatic breast cancer in the bones or bone metastases.